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Studies of membrane topology of mitochondrial cholesterol hydroxylases CYPs 27A1 and 11A1
Mitochondrial cytochrome P450 enzymes (CYP or P450, EC 1.14.13.15) play an important role in metabolism of cholesterol. CYP27A1 hydroxylates cholesterol at position 27 and, thus, initiates cholesterol removal from many extrahepatic tissues. CYP11A1 is a steroidogenic P450 that converts cholesterol t...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953644/ https://ncbi.nlm.nih.gov/pubmed/18791760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-008-3234-x |
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