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Isolevuglandins and Mitochondrial Enzymes in the Retina: MASS SPECTROMETRY DETECTION OF POST-TRANSLATIONAL MODIFICATION OF STEROL-METABOLIZING CYP27A1
We report the first peptide mapping and sequencing of an in vivo isolevuglandin-modified protein. Mitochondrial cytochrome P450 27A1 (CYP27A1) is a ubiquitous multifunctional sterol C27-hydroxylase that eliminates cholesterol and likely 7-ketocholesterol from the retina and many other tissues. We in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121529/ https://ncbi.nlm.nih.gov/pubmed/21498512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.232546 |
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