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Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1

The retina is the sensory organ in the back of the eye which absorbs and converts light to electrochemical impulses transferred to the brain. Herein, we studied how retinal environment affects enzyme-mediated cholesterol removal. We focused on two mitochondrial cytochrome P450 enzymes, CYPs 27A1 and...

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Detalhes bibliográficos
Main Authors: Heo, Gun-Young, Liao, Wei-Li, Turko, Illarion V., Pikuleva, Irina A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274590/
https://ncbi.nlm.nih.gov/pubmed/22227097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.12.016
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