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Upregulation of the rat cardiac sodium channel by in vivo treatment with a class I antiarrhythmic drug.
Class I antiarrhythmic drugs inhibit the sodium channel by binding to a drug receptor associated with the channel. In this report we show that in vivo administration of the class I antiarrhythmic drug mexiletine to rats induces sodium channel upregulation in isolated cardiac myocytes. The number of...
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| Udgivet i: | J Clin Invest |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1650791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115313 |
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