Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

Small interfering RNAs (siRNAs) direct RNA interference (RNAi) in eukaryotes. In flies, somatic cells produce siRNAs from exogenous double-stranded RNA (dsRNA) as a defense against viral infection. We identified endogenous siRNAs (endo-siRNAs), 21 nucleotides in length, that correspond to transposon...

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Main Authors: Ghildiyal, Megha, Seitz, Hervé, Horwich, Michael D., Li, Chengjian, Du, Tingting, Lee, Soohyun, Xu, Jia, Kittler, Ellen L.W., Zapp, Maria L., Weng, Zhiping, Zamore, Phillip D.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953241/
https://ncbi.nlm.nih.gov/pubmed/18403677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1157396
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