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Argonaute loading contributes to the precision of the 5′ ends of both microRNAs and their miRNA* strands in flies
MicroRNAs (miRNAs) are short (~21–23 nt) regulatory RNAs that direct repression of their mRNA targets. The miRNA “seed”—nucleotides 2 through 7—establishes miRNA target specificity, because small silencing RNAs bind their targets through this region [1-5]. Accurate processing of the miRNA 5′ end is...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854039/ https://ncbi.nlm.nih.gov/pubmed/18207740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.12.049 |
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