Without Argonaute3, Aubergine-bound piRNAs collapse but Piwi-bound piRNAs persist

Piwi-interacting RNAs (piRNAs) silence transposons in the germ line of animals. They are thought to derive from long primary transcripts spanning transposon-rich genomic loci, “piRNA clusters.” piRNAs are proposed to direct an auto-amplification loop in which an antisense piRNA, bound to Aubergine o...

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Autores principales: Li, Chengjian, Vagin, Vasily V., Lee, Soohyun, Xu, Jia, Ma, Shengmei, Xi, Hualin, Seitz, Hervé, Horwich, Michael D., Syrzycka, Monika, Honda, Barry M., Kittler, Ellen L.W., Zapp, Maria L., Klattenhoff, Carla, Schulz, Nadine, Theurkauf, William E., Weng, Zhiping, Zamore, Phillip D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768572/
https://ncbi.nlm.nih.gov/pubmed/19395009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.04.027
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