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Hepatitis C Virus Egress and Release Depend on Endosomal Trafficking of Core Protein

Hepatitis C virus (HCV) assembly is known to occur in juxtaposition to lipid droplets, but the mechanisms of nascent virion transport and release remain poorly understood. Here we demonstrate that HCV core protein targets to early and late endosomes but not to mitochondria or peroxisomes. Further, b...

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Bibliografiske detaljer
Main Authors: Lai, Chao-Kuen, Jeng, King-Song, Machida, Keigo, Lai, Michael M. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953145/
https://ncbi.nlm.nih.gov/pubmed/20739534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00587-10
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