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Nonstructural Protein 5A Is Incorporated into Hepatitis C Virus Low-Density Particle through Interaction with Core Protein and Microtubules during Intracellular Transport

Nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) serves dual functions in viral RNA replication and virus assembly. Here, we demonstrate that HCV replication complex along with NS5A and Core protein was transported to the lipid droplet (LD) through microtubules, and NS5A-Core complexes wer...

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Detaylı Bibliyografya
Asıl Yazarlar: Lai, Chao-Kuen, Saxena, Vikas, Tseng, Chung-Hsin, Jeng, King-Song, Kohara, Michinori, Lai, Michael M. C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048239/
https://ncbi.nlm.nih.gov/pubmed/24905011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099022
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