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Nuclear Import of Cytoplasmic Poly(A) Binding Protein Restricts Gene Expression via Hyperadenylation and Nuclear Retention of mRNA

Poly(A) tail length is emerging as an important marker of mRNA fate, where deviations from the canonical length can signal degradation or nuclear retention of transcripts. Pathways regulating polyadenylation thus have the potential to broadly influence gene expression. Here we demonstrate that accum...

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Détails bibliographiques
Auteurs principaux: Kumar, G. Renuka, Glaunsinger, Britt A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953054/
https://ncbi.nlm.nih.gov/pubmed/20823266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00600-10
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