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Importin α-Mediated Nuclear Import of Cytoplasmic Poly(A) Binding Protein Occurs as a Direct Consequence of Cytoplasmic mRNA Depletion

Recent studies have found the cytoplasmic poly(A) binding protein (PABPC) to have opposing effects on gene expression when concentrated in the cytoplasm versus in the nucleus. PABPC is predominantly cytoplasmic at steady state, where it enhances protein synthesis through simultaneous interactions wi...

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Main Authors: Kumar, G. Renuka, Shum, Leona, Glaunsinger, Britt A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147611/
https://ncbi.nlm.nih.gov/pubmed/21646427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05402-11
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