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The Human Nuclear Poly(A)-Binding Protein Promotes RNA Hyperadenylation and Decay

Control of nuclear RNA stability is essential for proper gene expression, but the mechanisms governing RNA degradation in mammalian nuclei are poorly defined. In this study, we uncover a mammalian RNA decay pathway that depends on the nuclear poly(A)-binding protein (PABPN1), the poly(A) polymerases...

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Bibliografski detalji
Glavni autori: Bresson, Stefan M., Conrad, Nicholas K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798265/
https://ncbi.nlm.nih.gov/pubmed/24146636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003893
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