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The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 ‘gate’

The Mcm2-7 complex is the eukaryotic replicative helicase, a toroidal AAA(+) molecular motor that uses adenosine triphosphate (ATP) binding and hydrolysis to separate duplex DNA strands during replication. This heterohexameric helicase contains six different and essential subunits (Mcm2 through Mcm7...

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Bibliografske podrobnosti
Main Authors: Bochman, Matthew L., Schwacha, Anthony
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952866/
https://ncbi.nlm.nih.gov/pubmed/20484375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq422
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