Mixed Backbone Antisense Glucosylceramide Synthase Oligonucleotide (MBO-asGCS) loaded Solid Lipid Nanoparticles: In Vitro Characterization and Reversal of Multidrug Resistance in NCI/ADR-RES Cells

In this study, Solid Lipid Nanoparticles (SLN) loaded with MBO-asGCS oligonucleotide were prepared, characterized and evaluated for cytotoxicity against NCI/ADR-RES human ovary cancer cells. Two types of cetyl trimethy ammonium bromide (CTAB) stabilized SLN, with or without ceramideVI, were prepared...

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Hlavní autoři: Siddiqui, Akhtar, Patwardhan, Gauri Anand, Liu, Young-Yu, Nazzal, Sami
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952652/
https://ncbi.nlm.nih.gov/pubmed/20816930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.08.044
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