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Mixed Backbone Antisense Glucosylceramide Synthase Oligonucleotide (MBO-asGCS) loaded Solid Lipid Nanoparticles: In Vitro Characterization and Reversal of Multidrug Resistance in NCI/ADR-RES Cells
In this study, Solid Lipid Nanoparticles (SLN) loaded with MBO-asGCS oligonucleotide were prepared, characterized and evaluated for cytotoxicity against NCI/ADR-RES human ovary cancer cells. Two types of cetyl trimethy ammonium bromide (CTAB) stabilized SLN, with or without ceramideVI, were prepared...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952652/ https://ncbi.nlm.nih.gov/pubmed/20816930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.08.044 |
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