Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma.
The expression of the insulin-like growth factors (IGFs) and their receptors has been linked to cellular proliferation and tumorigenicity in a number of model systems. Since rhabdomyosarcoma cells express IGF-I receptors, an autocrine or paracrine loop involving this receptor and its ligands could b...
Сохранить в:
| Опубликовано в:: | J Clin Invest |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
1994
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8083365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117441 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|