Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma.

The expression of the insulin-like growth factors (IGFs) and their receptors has been linked to cellular proliferation and tumorigenicity in a number of model systems. Since rhabdomyosarcoma cells express IGF-I receptors, an autocrine or paracrine loop involving this receptor and its ligands could b...

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I whakaputaina i:	J Clin Invest
Ngā kaituhi matua:	Shapiro, D N, Jones, B G, Shapiro, L H, Dias, P, Houghton, P J
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	American Society for Clinical Investigation 1994
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8083365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117441
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