Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma.

The expression of the insulin-like growth factors (IGFs) and their receptors has been linked to cellular proliferation and tumorigenicity in a number of model systems. Since rhabdomyosarcoma cells express IGF-I receptors, an autocrine or paracrine loop involving this receptor and its ligands could b...

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Main Authors: Shapiro, D N, Jones, B G, Shapiro, L H, Dias, P, Houghton, P J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295208/
https://ncbi.nlm.nih.gov/pubmed/8083365
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