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Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques
Maternal HIV-1-specific antibodies are efficiently transferred to newborns; their role in disease control is unknown. We administered non-sterilizing levels of neutralizing IgG, including the human neutralizing monoclonal IgG1b12, to six newborn macaques before oral challenge with SHIV(SF612P3). All...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952052/ https://ncbi.nlm.nih.gov/pubmed/20890292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2233 |
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