Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

It is widely appreciated that effective human vaccines directed against viral pathogens elicit neutralizing antibodies (NAbs). The passive transfer of anti–HIV-1 NAbs conferring sterilizing immunity to macaques has been used to determine the plasma neutralization titers, which must be present at the...

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Main Authors: Shingai, Masashi, Donau, Olivia K., Plishka, Ronald J., Buckler-White, Alicia, Mascola, John R., Nabel, Gary J., Nason, Martha C., Montefiori, David, Moldt, Brian, Poignard, Pascal, Diskin, Ron, Bjorkman, Pamela J., Eckhaus, Michael A., Klein, Florian, Mouquet, Hugo, Cetrulo Lorenzi, Julio Cesar, Gazumyan, Anna, Burton, Dennis R., Nussenzweig, Michel C., Martin, Malcolm A., Nishimura, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172223/
https://ncbi.nlm.nih.gov/pubmed/25155019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132494
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