Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques

Maternal HIV-1-specific antibodies are efficiently transferred to newborns; their role in disease control is unknown. We administered non-sterilizing levels of neutralizing IgG, including the human neutralizing monoclonal IgG1b12, to six newborn macaques before oral challenge with SHIV(SF612P3). All...

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Detalhes bibliográficos
Main Authors: Ng, Cherie T., Jaworski, J. Pablo, Jayaraman, Pushpa, Sutton, William F., Delio, Patrick, Kuller, LaRene, Anderson, David, Landucci, Gary, Richardson, Barbra A., Burton, Dennis R., Forthal, Donald N., Haigwood, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952052/
https://ncbi.nlm.nih.gov/pubmed/20890292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2233
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