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Impaired Activation-induced Cell Death Promotes Spontaneous Arthritis in Antigen (Cartilage Proteoglycan)-Specific T Cell Receptor Transgenic Mice
OBJECTIVE: We performed a longitudinal study using BALB/c mice expressing a T cell receptor (TCR) recognizing the arthritogenic ATEGRVRVNSAYQDK peptide of human cartilage proteoglycan (PG) to determine whether this genetic preponderance is sufficient for the development of arthritis. METHODS: PG-spe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952044/ https://ncbi.nlm.nih.gov/pubmed/20564001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27614 |
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