FTY720 (Gilenya) treatment prevents spontaneous autoimmune myocarditis and dilated cardiomyopathy in transgenic HLA-DQ8-BALB/c mice

Although dilated cardiomyopathy (DCM) is often caused by viral infections, it frequently involves autoimmune mechanisms associated with particular HLA-DR and DQ alleles. Our homozygous HLA-DQ8.Ab(0) transgenic mice in the BALB/c background (HLA-DQ8(BALB/c)-Tg) developed early and progressive fatal h...

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Dettagli Bibliografici
Pubblicato in:Cardiovasc Pathol
Autori principali: Boldizsar, Ferenc, Tarjanyi, Oktavia, Olasz, Katalin, Hegyi, Akos, Mikecz, Katalin, Glant, Tibor T., Rauch, Tibor A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372700/
https://ncbi.nlm.nih.gov/pubmed/27288745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2016.05.003
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