Impaired Activation-induced Cell Death Promotes Spontaneous Arthritis in Antigen (Cartilage Proteoglycan)-Specific T Cell Receptor Transgenic Mice

OBJECTIVE: We performed a longitudinal study using BALB/c mice expressing a T cell receptor (TCR) recognizing the arthritogenic ATEGRVRVNSAYQDK peptide of human cartilage proteoglycan (PG) to determine whether this genetic preponderance is sufficient for the development of arthritis. METHODS: PG-spe...

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Auteurs principaux: Boldizsar, Ferenc, Kis-Toth, Katalin, Tarjanyi, Oktavia, Olasz, Katalin, Hegyi, Akos, Mikecz, Katalin, Glant, Tibor T.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952044/
https://ncbi.nlm.nih.gov/pubmed/20564001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27614
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