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Prion Strain Interactions Are Highly Selective

Various misfolded and aggregated neuronal proteins commonly coexist in neurodegenerative disease, but whether the proteins coaggregate and alter the disease pathogenesis is unclear. Here, we used mixtures of distinct prion strains, which are believed to differ in conformation, to test the hypothesis...

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Hlavní autoři: Nilsson, K. Peter R., Joshi-Barr, Shivanjali, Winson, Olivia, Sigurdson, Christina J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951977/
https://ncbi.nlm.nih.gov/pubmed/20826672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2417-10.2010
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