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Chemical and biophysical insights into the propagation of prion strains

Transmissible spongiform encephalopathies (TSEs) are lethal infectious neurodegenerative diseases. TSEs are caused by prions, infectious agents lacking informational nucleic acids, and possibly identical with higher-order aggregates of the cellular glycolipoprotein PrP(C). Prion strains are derived...

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Detalhes bibliográficos
Main Authors: Falsig, Jeppe, Nilsson, K. PeterR., Knowles, Tuomas P. J., Aguzzi, Adriano
Formato: Artigo
Idioma:Inglês
Publicado em: HFSP Publishing 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645583/
https://ncbi.nlm.nih.gov/pubmed/19436493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.2990786
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