Human FANCC is hypomorphic in murine Fancc-deficient cells

Fancc suppresses cross-linker–induced genotoxicity, modulates growth-inhibitory cytokine responses, and modulates endotoxin responses. Although loss of the latter function is known to account for endotoxin-induced marrow failure in murine Fancc (mFancc)–deficient mice, some argue that cytokine and e...

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Autori principali: Hays, Laura E., Keeble, Winifred W., Yates, Jane E., Rathbun, R. K., Koretsky, Tara, Olson, Susan B., Sun, Zejin, Clapp, D. Wade, Bagby, Grover C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951854/
https://ncbi.nlm.nih.gov/pubmed/20554974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-266411
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