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Intracellular Trafficking and Decondensation Kinetics of Chitosan–pDNA Polyplexes
The transfection efficiency (TE) of chitosan–plasmid DNA (pDNA) polyplexes can be critically modulated by the polymer degree of deacetylation (DDA) and molecular weight (MW). This study was performed to test the hypothesis that the TE dependence on chitosan MW and DDA is related to the polyplex stab...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951560/ https://ncbi.nlm.nih.gov/pubmed/20628361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.143 |
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