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Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

[Image: see text] The development and thorough characterization of nonviral delivery agents for nucleic acid and genome editing therapies are of high interest to the field of nanomedicine. Indeed, this vehicle class offers the ability to tune chemical architecture/biological activity and readily pac...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Tolstyka, Zachary P., Phillips, Haley, Cortez, Mallory, Wu, Yaoying, Ingle, Nilesh, Bell, Jason B., Hackett, Perry B., Reineke, Theresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710891/
https://ncbi.nlm.nih.gov/pubmed/26807438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.5b00312
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