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Spatio-Temporal Cellular Imaging of Polymer-pDNA Nanocomplexes Affords In Situ Morphology and Trafficking Trends

Synthetic polymers are ubiquitous in the development of drug and polynucleotide delivery vehicles, offering promise for personalized medicine. However, the polymer structure plays a central yet elusive role in dictating the efficacy, safety, mechanisms, and kinetics of therapeutic transport in a spa...

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Detalhes bibliográficos
Main Authors: Ingle, Nilesh P., Lian, Xue, Reineke, Theresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967858/
https://ncbi.nlm.nih.gov/pubmed/24007201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp400115y
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