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Enhanced Gene Delivery Mediated by Low Molecular Weight Chitosan/DNA Complexes: Effect of pH and Serum

This study was designed to systematically evaluate the influence of pH and serum on the transfection process of chitosan–DNA complexes, with the objective of maximizing their efficiency. The hydrodynamic diameter of the complexes, measured by dynamic light scattering (DLS), was found to increase wit...

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Detalhes bibliográficos
Main Authors: Nimesh, Surendra, Thibault, Marc M., Lavertu, Marc, Buschmann, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Humana Press Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929434/
https://ncbi.nlm.nih.gov/pubmed/20454872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-010-9286-1
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