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Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1

Accumulating evidence suggests that spinal astrocytes play an important role in the genesis of persistent pain, by increasing the activity of spinal cord nociceptive neurons, i.e., central sensitization. But direct evidence of whether activation of astrocytes is sufficient to induce chronic pain sym...

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Bibliografiske detaljer
Main Authors: Gao, Yong-Jing, Zhang, Ling, Ji, Ru-Rong
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951489/
https://ncbi.nlm.nih.gov/pubmed/20737477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21056
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