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Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1

BACKGROUND: Paclitaxel is a widely used and potent chemotherapeutic agent for the treatment of cancer. However, patients receiving paclitaxel often develop an acute pain syndrome for which there are few treatment options. Astrocytes play an important role in the pathogenesis of pain in multiple prec...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Liu, Xiaojuan, Tonello, Raquel, Ling, Yuejuan, Gao, Yong-Jing, Berta, Temugin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842526/
https://ncbi.nlm.nih.gov/pubmed/31707979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1619-9
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