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Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1

BACKGROUND: Paclitaxel is a widely used and potent chemotherapeutic agent for the treatment of cancer. However, patients receiving paclitaxel often develop an acute pain syndrome for which there are few treatment options. Astrocytes play an important role in the pathogenesis of pain in multiple prec...

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Podrobná bibliografie
Vydáno v:J Neuroinflammation
Hlavní autoři: Liu, Xiaojuan, Tonello, Raquel, Ling, Yuejuan, Gao, Yong-Jing, Berta, Temugin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842526/
https://ncbi.nlm.nih.gov/pubmed/31707979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1619-9
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