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Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1

Accumulating evidence suggests that spinal astrocytes play an important role in the genesis of persistent pain, by increasing the activity of spinal cord nociceptive neurons, i.e., central sensitization. But direct evidence of whether activation of astrocytes is sufficient to induce chronic pain sym...

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Detalhes bibliográficos
Main Authors: Gao, Yong-Jing, Zhang, Ling, Ji, Ru-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951489/
https://ncbi.nlm.nih.gov/pubmed/20737477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21056
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