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Effect of Vitamin K-dependent Protein Precursor Propeptide, Vitamin K Hydroquinone, and Glutamate Substrate Binding on the Structure and Function of γ-Glutamyl Carboxylase

The γ-glutamyl carboxylase utilizes four substrates to catalyze carboxylation of certain glutamic acid residues in vitamin K-dependent proteins. How the enzyme brings the substrates together to promote catalysis is an important question in understanding the structure and function of this enzyme. The...

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Bibliographische Detailangaben
Hauptverfasser: Higgins-Gruber, Shannon L., Mutucumarana, Vasantha P., Lin, Pen-Jen, Jorgenson, James W., Stafford, Darrel W., Straight, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951224/
https://ncbi.nlm.nih.gov/pubmed/20716530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.143297
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