A hetero-dimer model for concerted action of vitamin K carboxylase and vitamin K reductase in vitamin K cycle

Vitamin K carboxylase (VKC) is believed to convert vitamin K, in the vitamin K cycle, to an alkoxide-epoxide form which then reacts with CO(2) and glutamate to generate γ-carboxyglutamic acid (Gla). Subsequently, vitamin K epoxide reductase (VKOR) is thought to convert the alkoxide-epoxide to a hydr...

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Bibliografiske detaljer
Main Authors: Wu, Sangwook, Liu, Shubin, Davis, Charles H., Stafford, Darrel W., Kulman, J. D., Pedersen, Lee G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108363/
https://ncbi.nlm.nih.gov/pubmed/21453708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2011.03.030
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