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Cutting Edge: T cell receptor ligation triggers digital activation of NF-κB
T cell receptor (TCR) mediated activation of the transcription factor NF-κB is required for T cell proliferation, survival, and effector differentiation. Although this pathway is the subject of intense study, it is not known whether TCR signaling to NF-κB is digital (switch-like) or analog in nature...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950878/ https://ncbi.nlm.nih.gov/pubmed/20855880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001051 |
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