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C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses

The C-type lectin receptors (CLRs) belong to a large family of proteins that contain a carbohydrate recognition domain (CRD) and calcium binding sites on their extracellular domains. Recent studies indicate that many CLRs, such as Dectin-1, Dectin-2 and Mincle, function as pattern recognition recept...

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Bibliographic Details
Main Authors: Kingeter, Lara M, Lin, Xin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002809/
https://ncbi.nlm.nih.gov/pubmed/22246129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.58
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