α(7)-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis

Controlled clinical trials of nicotine transdermal patch for treatment of ulcerative colitis have been shown to improve histological and global clinical scores of colitis. Here we report that nicotine (1 μM) suppresses in vitro hyperexcitability of colonic dorsal root ganglia (DRG) (L(1)–L(2)) neuro...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Abdrakhmanova, Galya R., AlSharari, Shakir, Kang, Minho, Damaj, M. Imad, Akbarali, Hamid I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
Neuroregulation and Motility
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950695/
https://ncbi.nlm.nih.gov/pubmed/20595621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00175.2010
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky