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Structures of RNA polymerase-antibiotic complexes

Inhibition of bacterial RNA polymerase (RNAP) is an established strategy for antituberculosis therapy and broad-spectrum antibacterial therapy. Crystal structures of RNAP-inhibitor complexes are available for four classes of antibiotics: rifamycins, sorangicin, streptolydigin, and myxopyronin. The s...

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書誌詳細
主要な著者: Ho, Mary X., Hudson, Brian P., Das, Kalyan, Arnold, Eddy, Ebright, Richard H.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950656/
https://ncbi.nlm.nih.gov/pubmed/19926275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.10.010
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