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Structures of RNA polymerase-antibiotic complexes
Inhibition of bacterial RNA polymerase (RNAP) is an established strategy for antituberculosis therapy and broad-spectrum antibacterial therapy. Crystal structures of RNAP-inhibitor complexes are available for four classes of antibiotics: rifamycins, sorangicin, streptolydigin, and myxopyronin. The s...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950656/ https://ncbi.nlm.nih.gov/pubmed/19926275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.10.010 |
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