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The Type I Interferon Signaling Pathway Is a Target for Glucocorticoid Inhibition
Type I interferon (IFN) is essential for host defenses against viruses; however, dysregulated IFN signaling is causally linked to autoimmunity, particularly systemic lupus erythematosus. Autoimmune disease treatments rely on glucocorticoids (GCs), which act via the GC receptor (GR) to repress proinf...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950533/ https://ncbi.nlm.nih.gov/pubmed/20679482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00146-10 |
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