Identification of the TcpP-Binding Site in the toxT Promoter of Vibrio cholerae and the Role of ToxR in TcpP-Mediated Activation

ToxR-dependent recruitment of TcpP to the toxT promoter facilitates toxT transcription in Vibrio cholerae, initiating a regulatory cascade that culminates in cholera toxin expression and secretion. Although TcpP usually requires ToxR to activate the toxT promoter, TcpP overexpression can circumvent...

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Main Authors: Goss, Thomas J., Seaborn, Craig P., Gray, Miranda D., Krukonis, Eric S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
主題:
Molecular Pathogenesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950353/
https://ncbi.nlm.nih.gov/pubmed/20679441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00566-10
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