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Formation of an Intramolecular Periplasmic Disulfide Bond in TcpP Protects TcpP and TcpH from Degradation in Vibrio cholerae

TcpP and ToxR coordinately regulate transcription of toxT, the master regulator of numerous virulence factors in Vibrio cholerae. TcpP and ToxR are membrane-localized transcription factors, each with a periplasmic domain containing two cysteines. In ToxR, these cysteines form an intramolecular disul...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Morgan, Sarah J., French, Emily L., Thomson, Joshua J., Seaborn, Craig P., Shively, Christian A., Krukonis, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719457/
https://ncbi.nlm.nih.gov/pubmed/26574510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00338-15
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