ToxR Recognizes a Direct Repeat Element in the toxT, ompU, ompT, and ctxA Promoters of Vibrio cholerae To Regulate Transcription

ToxR facilitates TcpP-mediated activation of the toxT promoter in Vibrio cholerae, initiating a regulatory cascade that culminates in cholera toxin secretion and toxin coregulated pilus expression. ToxR binds a region from −104 to −68 of the toxT promoter, from which ToxR recruits TcpP to the TcpP-b...

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Bibliographic Details
Main Authors: Goss, Thomas J., Morgan, Sarah J., French, Emily L., Krukonis, Eric S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584884/
https://ncbi.nlm.nih.gov/pubmed/23297386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00889-12
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