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Single-molecule tracking in live Vibrio cholerae reveals that ToxR recruits the membrane-bound virulence regulator TcpP to the toxT promoter

Vibrio cholerae causes the human disease cholera by producing a potent toxin. The V. cholerae virulence pathway involves an unusual transcription step: the bitopic inner-membrane proteins TcpP and ToxR activate toxT transcription. As ToxT is the primary direct transcription activator in V. cholerae...

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Bibliographic Details
Published in:Mol Microbiol
Main Authors: Haas, Beth L., Matson, Jyl S., DiRita, Victor J., Biteen, Julie S.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025817/
https://ncbi.nlm.nih.gov/pubmed/25318589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12834
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