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MEK/ERK-Mediated Phosphorylation of Bim is Required to Ensure Survival of T and B Lymphocytes during Mitogenic Stimulation
Survival and death of lymphocytes is regulated by the balance between pro- and anti-apoptotic members of the Bcl-2 family, and this is coordinated with the control of cell cycling and differentiation. Bim, a pro-apoptotic BH3-only member of the Bcl-2 family, can be regulated by MEK/ERK-mediated phos...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950174/ https://ncbi.nlm.nih.gov/pubmed/19542438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803853 |
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