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Endogenous bcl-2 is not required for the development of Eμ-myc–induced B-cell lymphoma

Although myc and bcl-2 synergize in tumor development, particularly lymphomagenesis, it is not known whether endogenous bcl-2 is required for myc-induced tumorigenesis. To investigate the role of endogenous Bcl-2 in myc-induced lymphomagenesis, we bypassed the early death of Bcl-2–deficient mice by...

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Bibliografske podrobnosti
Main Authors: Kelly, Priscilla N., Puthalakath, Hamsa, Adams, Jerry M., Strasser, Andreas
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885522/
https://ncbi.nlm.nih.gov/pubmed/17317859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-051847
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