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Endogenous Bcl-x(L) is essential for Myc-driven lymphomagenesis in mice
Impaired apoptosis is a cancer hallmark, and some types of lymphomas and other cancers harbor mutations that directly affect key cell death regulators, such as Bcl-2 family members. However, because the majority of tumors seem to lack such mutations, we are examining the hypothesis that tumorigenesi...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3236120/ https://ncbi.nlm.nih.gov/pubmed/21998213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-367672 |
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