Endogenous Bcl-x(L) is essential for Myc-driven lymphomagenesis in mice

Impaired apoptosis is a cancer hallmark, and some types of lymphomas and other cancers harbor mutations that directly affect key cell death regulators, such as Bcl-2 family members. However, because the majority of tumors seem to lack such mutations, we are examining the hypothesis that tumorigenesi...

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Bibliografiset tiedot
Päätekijät: Kelly, Priscilla N., Grabow, Stephanie, Delbridge, Alex R. D., Strasser, Andreas, Adams, Jerry M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2011
Aiheet:
Lymphoid Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236120/
https://ncbi.nlm.nih.gov/pubmed/21998213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-367672
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